Rural area的問題，透過圖書和論文來找解法和答案更準確安心。 我們挖掘出下列價位、菜單、推薦和訂位總整理

Struggling with God: Mental Health and Christian Spirituality

為了解決Rural area的問題，作者Cook, Christopher C. H.,Hamley, Isabelle,Swinton, John 這樣論述：

Christopher C. H. Cook is Professor of Spirituality, Theology & Health at Durham University. He worked as a psychiatrist in the NHS for over 25 years before retiring from clinical practice, and was ordained as an Anglican priest in 2001. He ministers in a small rural parish in the Yorkshire Dales. H

is books include Spirituality, Theology and Mental Health (2013), Hearing Voices, Demonic and Divine (2018), and (with Isabelle Hamley) The Bible and Mental Health (2020). Isabelle Hamley is Theological Adviser to the House of Bishops and was formerly Chaplain to the Archbishop of Canterbury. She ha

s long been concerned with questions of justice, mercy and restoration, having been a probation officer before ordination and ministering subsequently amidst the diversity of parish life. Her books include (with Christopher C. Cook) The Bible and Mental Health (2020), and Unspeakable Things Spoken (

2019) and Embracing Justice: The Archbishop of Canterbury’s Lent Book 2022.John Swinton is Professor in Practical Theology and Pastoral Care and Chair in Divinity and Religious Studies at the University of Aberdeen. For more than a decade John worked as a registered mental health nurse, then as a ch

aplain alongside people with severe mental health challenges who were moving from the hospital into the community. In 2004, he founded the University of Aberdeen’s Centre for Spirituality, Health and Disability. He has published widely within the area of mental health, dementia, disability theology,

spirituality and healthcare, qualitative research and pastoral care. John is the author of a number of monographs including Finding Jesus in the Storm: The spiritual lives of people with mental health challenges. (Eerdmans 2020). His book Dementia: Living in the memories of God won the Michael Rams

ey Prize for excellence in theological writing.

Rural area進入發燒排行的影片

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Rural area的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.

Secret Northwich & Around

為了解決Rural area的問題，作者Bridge, Adrian And Dawn 這樣論述：

Through much of its history the Cheshire town of Northwich was little more than six statutory acres. This modest settlement was surrounded by other small townships, which it gradually absorbed over time. The bonds between central Northwich and its surrounding villages and settlements have been ve

ry strong for centuries. The long industrial history of parts of Northwich - famous for its salt, soda ash and shipbuilding - contrast with the semi-rural character of areas such as Davenham and Hartford.In ’Secret Northwich & Around’, local authors Adrian and Dawn L. Bridge delve beneath the su

rface of the area’s fascinating history and focus upon aspects of its past that are lesser-known, but of considerable significance. Among the subjects highlighted is the massive impact that slave trade money had on the local economy. Other chapters look at local industries, people, power and controv

ersy and Victorian politics. The authors also explore hidden aspects of the locality’s past, which include topics ranging from law and order to public health and poverty, and religion to wartime.Illustrated throughout, with colour and archive images, this book will be of interest to local residents,

visitors and all those with connections to the area.

台中港區微粒、金屬元素之乾沉降污染物預測、排放來源及健康風險評估之研究

為了解決Rural area的問題，作者高偉順 這樣論述：

本研究是使用PS-1採樣器與乾沉降板來蒐集大氣中的懸浮微粒及其附屬重金屬汙染物之濃度及乾沉降，採樣時間於2020年1月至12月於台中梧棲港區來進行。本研究並藉由使用ICP-OES分析儀來分析附著於懸浮微粒上之汙染物的重金屬濃度及乾沉降。再者，本研究亦使用Global model來推估並比較不同粒徑所計算出來之懸浮微粒及其附屬重金屬汙染物之乾沉降通量，其值並與實際之乾沉降值作一比較。除此之外，本研究並利用逆軌跡分析方法來推測台中港區採樣點之可能汙染源。最後，本研究更以風險評估之方法來計算該特徵採樣點之致癌風險值。研究結果顯示，總懸浮微粒濃度與乾沉降通量其最高值均發生於冬季，而重金屬濃度與乾沉降

之最高值則分別為重金屬Cu，Ni。此外，乾沉降模式之研究結果顯示，Global collection model之模式推估乾沉降通量以重金屬元素Pb可得到最佳之乾沉降推估結果。再者，重金屬元素Pb 乾沉降通量之最佳預測結果則出現在 以16 μm 的微粒尺寸作為計算之乾沉降速度則其乾沉降通量能有最佳之推估結果。而逆軌跡分析之結果顯示，本研究之主要汙染氣團於6、7、8月是來自採樣點的南方，其餘月份皆來自於採樣點之北方。而在健康風險評估結果顯示該採樣點之金屬元素Cr的致癌風險值結果高於1×10-4，上述值高於致癌風險監管機構US/EPA之標準。因此，未來宜持續監測觀察上述重金屬Cr元素於台中港區之濃

度及致癌風險值。